A huge crowd has blocked one of the busiest thoroughfares in Melbourne during a protest against what they say is the "unjust" verdict handed to a man who killed Aboriginal teenager Elijah Doughty.

Hundreds of protesters marched from the steps of Victoria's Parliament to Flinders St station.

They chanted "no justice, no peace" as they moved down Swanston Street, carrying banners and signs that said "black lives matter".

They then staged a sit-in, bringing the busy precinct to a standstill.

Elijah, 14, was riding a motorbike when he was chased and hit by the driver of a ute who said he had gone looking for two stolen motorbikes at a reserve in Kalgoorlie-Boulder, 600 kilometres east of Perth, in August last year.

The man behind the wheel, who cannot be identified, was cleared of manslaughter in the Perth Supreme Court and given a three-year sentence for the lesser charge of dangerous driving causing death.

The verdict prompted rallies in Sydney, Brisbane, Adelaide and Perth earlier this week.

The protesters blocked trams and traffic along Flinders St, Swanston St and Collins St during evening peak traffic.

After sunset, protesters sung as a man played the didgeridoo during a smoking ceremony.

Police said they were on scene monitoring the event.

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